Metastasis vs Spread

When to use each in English, with meaning, register, and examples.

Metastasis

FormalBeyond 10,000 (less common)

Spread

Top 1,000 (very common)B1verb
Most formal: MetastasisMost common: Spread
 MetastasisSpread
Pronunciation🇬🇧 //məˈtæstəsɪs//🇺🇸 //məˈtæstəsɪs//🇬🇧 /["/spred/","/spredz/","/ˈspredɪŋ/"]/🇺🇸 /["/spred/","/spredz/","/ˈspredɪŋ/"]/
MeaningSpread of cancer from one part of the body to another.To open something wide or make it cover a large area.
ExampleThe doctor explained that the metastasis of the tumor was concerning.She decided to spread the butter evenly on her toast.
RegisterFormalNeutral
How commonBeyond 10,000 (less common)Top 1,000 (very common)
CEFR level-B1
Part of speechverb
Collocationscancer metastasis, bone metastasis, metastasis to lymph nodesfast, like wildfire, quickly, (all) across, among, around, be thinly spread, spread yourself too thin, fast, like wildfire, quickly, (all) across, among, around, be thinly spread, spread yourself too thin, fast, like wildfire, quickly, (all) across, among, around, be thinly spread, spread yourself too thin, thickly, lightly, thinly, on, with, carefully, out, across, on, over, spread something open, spread your arms, legs, etc. out wide, spread your arms, legs, etc. wide, carefully, out, across, on, over, spread something open, spread your arms, legs, etc. out wide, spread your arms, legs, etc. wide, carefully, out, across, on, over, spread something open, spread your arms, legs, etc. out wide, spread your arms, legs, etc. wide, equally, evenly, uniformly, try to, among, between, over
Antonyms-conceal, gather, compress
Common mistakesConfused with 'metastatic', which describes the condition rather than the act., Mispronounced the term due to complex syllables., Used in casual conversation, which may be inappropriate.Confused with 'spred' as a past tense; the correct past is 'spread'., Misused with 'spreading out' when describing thoughts instead of physical spreading., Omitting the object; remember to include what is being spread.
Usage notesPrimarily used in medical contexts. It's important in discussions about cancer progression. Avoid using outside medical discussions.Use 'spread' when talking about applying something, like a sandwich spread or an idea. It's neutral and suitable for all contexts, but avoid using it too informally when discussing significant topics.

See it in real clips

Spread

Frequently asked questions: Metastasis vs Spread

What's the difference between Metastasis and Spread?

Metastasis: Spread of cancer from one part of the body to another. Spread: To open something wide or make it cover a large area.

Which is more formal: Metastasis and Spread?

Metastasis is the most formal of these.

Which is more common: Metastasis and Spread?

Spread is the most common in everyday English.

Can you show an example of each?

Metastasis: The doctor explained that the metastasis of the tumor was concerning. Spread: She decided to spread the butter evenly on her toast.

Can I use Metastasis and Spread interchangeably?

Not always. Metastasis and Spread are related and overlap in some contexts, but they differ in register, how common they are, and usage, so swapping one for another can change the meaning or tone. Check the differences above before substituting.