Drug vs Substance

When to use each in English, with meaning, register, and examples.

 DrugSubstance
MeaningA substance that can change how the body or mind works.A material or matter that has weight and takes up space.
CEFR levelA2B1
Part of speechnounnoun
Usage notesUsed in both medical and recreational contexts. Be careful with informal usage; it can sound negative or carry stigma. In formal contexts, it often refers to prescribed medications.Used in both scientific and everyday contexts to refer to physical materials or essential qualities. It’s not typically used in very informal speech.

Frequently asked questions: Drug vs Substance

What's the difference between "Drug" and "Substance"?

"Drug" means: A substance that can change how the body or mind works. "Substance" means: A material or matter that has weight and takes up space.

When should I use "Drug" and "Substance"?

They can all be used in everyday English.

Are "Drug" and "Substance" the same CEFR level?

"Drug" is at A2, "Substance" is at B1 on the CEFR scale.

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